GUTAMINOS for Horses | Targeted Nutritional Support for the Gut Lining & Intestinal Barrier

T o support any cellular repair in the body, we need protein, which is broken down into amino acids required for regeneration. And for a healthy gut membrane , two specific amino acids play a pivotal role in supporting the repair of this delicate tissue - L Glutamine and N-Acetyl L-Cysteine (NAC).

Now here's something I find fascinating. It's easy to think of "the gut" as a tube that digests food - but it's actually so much more than that.

The intestinal lining acts as one of the body's most important protective barriers, deciding what stays in, what gets absorbed, and how the immune system responds to the world passing through it every day.

And despite doing such an important job, it's only one single cell thick. Yes you read that right - just one cell thick. Remarkable, considering that that makes it extremely vulnerable to tears or ulcer wounds.

Those cells are constantly being renewed, repaired, and replaced - which means they have a very high demand for specific nutrients, particularly amino acids.

That's why nutrients such as L-Glutamine attract so much attention in both human and equine gut health discussions.

They're not there to "fix" the gut - they're there because the cells that make up the intestinal lining rely on them every day as part of their normal maintenance and renewal processes.

Supporting those processes can become particularly important following digestive upset - gastric ulcers or leaky gut (permeable membrane), periods of stress, gastric ulcer challenges, antibiotic use, or any situation where the gut's natural barrier may be under additional pressure.

GutAminos is a good fit when the focus shifts from what's happening inside the gut to the health of the gut lining itself.

✔ Your horse is recovering from gastric ulcers or ongoing stomach sensitivity
✔ Faecal water, loose droppings, or hindgut sensitivity suggest the intestinal barrier may need additional support
✔ Your horse is recovering after antibiotics, or stress
✔ You're supporting a horse with a history of gut challenges and want to nourish the tissues involved in repair and renewal
✔ The gut seems calmer than it was, but you're now thinking about rebuilding rather than stabilising
✔ You want targeted nutritional support for the cells that make up the intestinal lining
✔ You're looking beyond symptom management and thinking about long-term digestive resilience

In short: if your focus is supporting the health and renewal of the intestinal lining itself, GutAminos is the next step.

For many horses, GutAminos becomes the rebuilding phase of a wider digestive support plan – providing targeted nutritional support for the cells that form the body's most important digestive barrier.

From there, support can be adapted depending on what you're seeing.

- Building on a gut reset

• SiboCARE – where microbial imbalance, gas, bloating, or hindgut instability are still active parts of the picture.
• DuoBute – where discomfort, sensitivity, or gut-related tension are part of the picture alongside microbial imbalance,
• StressTonic - if your horse is stressed

For many horses, SiboCARE comes first, with GutAminos introduced once the gut environment has become calmer and more stable.

- Supporting gastric comfort

• UlsaTonic – where stomach sensitivity, gastric discomfort, or ulcer-related patterns are part of the picture.
• UlsaCOMBO – for horses needing broader support across gastric comfort, stress, and digestive resilience.

- Supporting the wider recovery picture

• LKLCARE – often used after digestive challenges to support the liver, kidneys, and wider internal housekeeping systems.
• LeakyGutCOMBO – where microbial balance and gut-lining support are both required within one combined programme.

- Foundation support

Healthy digestive tissues rely on more than targeted nutrients alone. Supporting your horse's baseline nutrition with a forage-based mineral blend such as VitaComplete or EquiVita, alongside appropriate fibre and forage intake, helps provide the nutritional foundations that the gut lining depends upon for normal maintenance and renewal.

*If you're not already feeding a mineral balancer, try one of our 1kg trial bags.

In summary

Use GutAminos when the focus turns to rebuilding and nourishing the gut lining itself. It's very much part of a gut reset programme and works alongside broader digestive support where additional resilience and recovery are needed.

GutAminos is a nutritional food supplement and not veterinary medicine. For more on this, see Dr Kellon's article - Nutrition is not 'Alternative' Therapy .

Composition Glossary

Each ingredient in GutAminos plays a targeted role in maintaining your horse’s stomach comfort where additional support for the intestinal lining and wider digestive tract is needed.

• L-Glutamine – The preferred fuel of enterocytes (gut-lining cells), L-Glutamine supports epithelial repair, maintains pH balance, and helps restore the intestinal barrier after stress, illness, or inflammation. Known as the 'glue' for tight junctions, it’s vital for resolving leaky gut and improving nutrient absorption.
• N-Acetyl L-Cysteine (NAC) – A bioavailable precursor to glutathione, the body’s master antioxidant. NAC protects gut and liver cells from oxidative stress, supports detoxification pathways, and works in tandem with L-Glutamine to enhance tissue regeneration.
• Althaea officinalis Radix – A mucilaginous herb rich in polysaccharides that coat, soothe, and protect the mucosal lining. Traditionally used for gastric ulcers, it helps calm irritation, supports epithelial growth, and strengthens the gut’s natural barrier function.

Feed guide

• 3g/100kg bodyweight per day, i.e. 15g for a 500kg horse.
• 1 level 15ml scoop = 15-grams.
• Amino acids manufactured to ISO, BP, USP & EP requirements and/or food grade specifications.

Energetic Architecture explains how the nutrients and herbs in a formula are structured to work together in a balanced and purposeful way.

GutAminos is built around a simple observation: before the gut lining can renew itself, it needs the raw materials to do so.

The intestinal barrier is one of the fastest-renewing tissues in the body, constantly replacing cells exposed to food, microbes, digestive acids, and the wear-and-tear of daily life. That renewal process relies heavily on specific nutrients, particularly amino acids.

Rather than focusing on microbial balance or digestive symptoms, GutAminos focuses on nourishing the tissues that form the gut barrier itself.

Think of it as providing the bricks and mortar needed for ongoing maintenance and renewal.

Functional intent

GutAminos is designed to support:

• Intestinal lining health and renewal
• Gut barrier resilience and integrity
• Cellular nutrition for digestive tissues
• Antioxidant protection during tissue renewal
• Long-term digestive resilience

The goal is to provide nutritional support for the cells that maintain the gut barrier itself.

Functional categories – gut lining support in action

Cellular fuel for intestinal renewal

L-Glutamine

Providing a key fuel source for enterocytes - the specialised cells that line the intestinal tract.

Antioxidant & cellular resilience

N-Acetyl L-Cysteine (NAC)

Supporting glutathione production and helping maintain cellular resilience during periods of digestive challenge and recovery.

Mucosal comfort & barrier support

Althaea officinalis

Providing soothing, mucilage-rich support for the delicate tissues that line the digestive tract.

Nutritional support for tissue maintenance

L-Glutamine, N-Acetyl L-Cysteine

Supplying key nutritional building blocks involved in the normal maintenance and renewal of digestive tissues.

Big picture

When we think about gut health, we tend to focus on what's inside the gut - the microbes, the feed, the droppings, the symptoms.

Yet all of that sits on top of a barrier that's only one cell thick.

That's an extraordinary amount of responsibility for such a delicate structure.

GutAminos was created to support that barrier directly, providing targeted nutritional support for the cells that form one of the body's most important protective surfaces.

Put simply, resilient guts are built one cell at a time.

Advisories

• Best fed alongside SiboCARE or UlsaTonic for comprehensive intestinal and gastric membrane support.
• Hydration is essential: Ensure horses have constant access to clean water, as amino acids and mucilaginous herbs increase cellular water demand.
• Safe for long-term use as part of ongoing gut health management, especially following antibiotic use, colic recovery, or chronic stress.

Contraindications

• Pregnant or nursing mares: Always seek veterinary guidance before feeding due to limited safety data for NAC and Althaea officinalis in reproductive stages.

Coming...