L GLUTAMINE *The cellular powerhouse for repair and resilience

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L-Glutamine is the most abundant amino acid in the body, and a powerhouse with it.

Known as the building block for proteins, it plays a pivotal role in regenerating new healthy cells, especially during critical illness, trauma, intestinal disease, starvation, excessive loss of lean body mass, or extreme endurance exercise.

Essential for tissue repair, supporting muscle recovery and preserving lean body mass, and is particularly renowned for enhancing the intestine’s protective mucosal lining.



Overview

Why glutamine matters for equine health

Glutamine is a conditionally essential amino acid and the most abundant one found in muscle tissue. Hard work and training can quickly deplete its levels, making it vital for supporting muscle recovery and protecting equine athletes during exercise. This same role has made glutamine a go-to supplement for human bodybuilders and weight trainers.

But glutamine isn’t just about muscles - it’s also essential for gut health. Low levels are closely linked to gut permeability and inflammation, which is why supplementation is a key part of addressing leaky gut. Glutamine is the preferred energy source for the cells lining the gut wall, helping to fuel their growth and repair. These new, healthy cells are crucial for restoring the intestinal wall and eliminating leaky gut. Plus, glutamine helps maintain the right pH balance, supporting a healthier digestive environment.

How quickly does glutamine work?

In human studies, glutamine supplementation often begins to show effects within 30 days, with significant gut lining repair occurring in about 12 weeks.

The perfect synergy: glutamine and NAC

Glutamine works hand-in-hand with N-Acetyl Cysteine (NAC) to encourage the production of glutathione, the body’s natural master antioxidant. Together, they provide powerful support for overall gut and cellular health.

We include our L-Glutamine as standard in our GutAminos and JointReflexa blends. See our Gut System and Joints & Mobility pages in the Advice Centre/A-Z Equine Condition for the latest updates.

Composition & Feed Guide

Composition

100% pure L-Glutamine p owder
- Organism used is Corynebacterium glutamicum

Feed Guide

Interestingly, the equine RDA is a bit ambiguous. Google it and you'll see anything from 9g to 36g per day, to a rounded tablespoon/day. As an example, f rom a human perspective for leaky gut repair, a small dose won't cut it - it's usually 15/20/30-grams per day.

For horses, generally, as a maintenance dose, 4 g/100kg bodyweight is recommended, so 20g/day for a 500kg horse.

  • 1-level 15ml scoop = 15g
  • Want a scoop? You can add a scoop to your basket during checkout.
  • Supplied in a resealable, food-grade foil pouch for freshness.

Footnotes

  • Human Grade.
  • UK certificate of analysis available on request.
  • ♻️ Eco Note: Our packaging is recyclable and refillable.
  • 🧊 Storage Tip: Store away from direct heat and moisture to preserve stability of the amino acid compound.

Clinical Considerations

Advisories

  • Always ensure good hydration and adequate forage to support healthy gut motility and absorption.
  • Suitable for long-term use as part of a balanced nutritional programme supporting gut integrity and muscle recovery.

Contraindications

  • Not recommended for pregnant or nursing mares (limited safety data).
  • Avoid use during acute infection or fever when protein metabolism is compromised.
  • Use cautiously in horses with advanced hepatic disease or urea-cycle disorders; consult your vet before use.
  • Do not combine with synthetic L-Glutamine HCL.


Copyright Notice

© EquiNatural 2025. All content is original work protected under copyright, and may not be re-published, duplicated, or rewritten for commercial use without permission.

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L GLUTAMINE *The cellular powerhouse for repair and resilience