AdrenaVIVE Veterinary Reference Extract

EquiNatural® | Botanical Nutritional Support for Post-Stress Recovery, HPA-Axis Balance & Adrenal-Nervous System Resilience

Organically grown • Human grade • Not veterinary medicine


1. Important Context for Veterinary Review

Chronic or prolonged stress in horses affects:

  • HPA-axis stability
  • cortisol regulation
  • catecholamine sensitivity
  • adrenal load
  • gut–brain interaction
  • neurovascular tone
  • immune signalling


Even after the external stressor ends, neuroendocrine dysregulation often persists. Horses may exhibit:

  • fatigue
  • emotional shutdown
  • low engagement
  • post-stress sensitivity
  • dullness or irritability
  • slow recovery


AdrenaVIVE is designed not for acute stress, but for the recovery window after stress has been addressed, offering nutritional herbal support for:

  • adrenal restoration
  • nervous system recalibration
  • emotional resilience
  • energy balance


It is not a treatment for adrenal insufficiency, anxiety, endocrine disease, or behavioural disorders. It should be introduced thoughtfully in horses on corticosteroids or CNS-active medication.


2. Product Summary

AdrenaVIVE is a post-stress adaptogenic botanical blend formulated to support:

  • adrenal recalibration after chronic stress
  • HPA-axis balance
  • emotional recovery
  • improved focus & mental clarity
  • nervous system nourishment
  • steady energy without stimulation
  • resilience during rehabilitation or post-illness recovery


It is a follow-on formula after StressTonic or OptimaCARE, used when the nervous system has moved past fight–flight, but requires rebuilding.


3. Clinical Rationale (Nutritional Mechanisms of Action)

HPA-Axis Modulation (Withania, Rhodiola, Schisandra)

  • support cortisol rhythm normalisation
  • maintain adrenal resilience
  • buffer catecholamine excess
  • nourish stress-related neurotransmitter depletion


Neurovascular & Cognitive Support (Ginkgo)

  • supports cerebral blood flow
  • may help clarify focus post-shutdown
  • balances neurovascular tone


Adrenal Glycyrrhizin Synergy (Liquorice Root — low dose)

  • may prolong endogenous cortisol half-life
  • supports adrenal recovery but contraindicated with exogenous steroids
  • provides mucosal and endocrine nourishment


Mineral-Rich Nervous System Support (Nettle, Oat Straw)

  • magnesium, silica, B-group co-factors
  • supports nerve sheath repair and calm metabolic tone


Adaptogenic Endocrine Modulation (Schisandra)

  • supports mitochondrial efficiency
  • stabilises stress-induced oxidative load
  • helps restore emotional and behavioural steadiness


Nutritional adaptogens do not “treat” adrenal disease, but support physiological balance during recovery.


4. Nutritional Indications (Non-Diagnostic)

AdrenaVIVE may be used nutritionally in horses showing:

  • lingering fatigue post-stress or post-illness
  • low emotional resilience despite stressor resolution
  • shutdown, dulled affect, or disengagement
  • post-rehab depletion
  • hormonal wobbliness linked to stress load
  • long-term tension that has settled but left the horse “flattened”
  • sensitivity after winter stressors, yard changes, or herd disruption


Not intended to treat adrenal insufficiency, anxiety disorders, behavioural pathology, or endocrine disease.


5. Composition (No Ratios Listed)

Botanical Safety Preface

Botanical adaptogens and endocrine-supportive herbs influence stress physiology. Individual responses vary with workload, environment, and prior stress load.


Herb Composition

  • Withania somnifera
  • Ginkgo biloba
  • Glycyrrhiza glabra radix
  • Urtica dioica folia
  • Avena sativa herba
  • Rhodiola rosea
  • Rosa canina
  • Schisandra chinensis


6. Herb Micro-Monographs (Technical)

Withania somnifera (Ashwagandha)
Adaptogen traditionally used for HPA-axis modulation, supporting calm metabolic tone and post-stress recovery.

Ginkgo biloba
Neurovascular botanical supporting oxygenation, mental clarity, and recovery from emotional shutdown.

Glycyrrhiza glabra (Liquorice Root)
Low-dose adrenal-modulating herb; may prolong endogenous cortisol activity. Not for use with exogenous steroids.

Urtica dioica / Avena sativa
Mineral-rich nutritives supporting nerve repair, endocrine balance, and cellular vitality.

Rhodiola rosea
Adaptogen that supports stamina, mitochondrial efficiency, and recovery from physical or emotional fatigue.

Rosa canina
Vitamin C and polyphenol-rich whole-food supporting adrenal nutrient demand and oxidative balance.

Schisandra chinensis
HPA-axis modulator supporting focus, resilience, and stress recovery.


7. Medication Considerations

Use under veterinary guidance when the horse is receiving:

  • Corticosteroids (prednisolone, dexamethasone, inhaled steroids)
    → Liquorice may prolong steroid effect.
  • Sedatives, anxiolytics, or CNS-active medications
    → adaptogens may influence arousal pathways.
  • Anti-hypertensive or circulatory medications
    → Ginkgo has mild vascular effects.
  • HPA-axis disorders or endocrine therapy
    → adaptogenic herbs affect cortisol rhythm.
  • Immunosuppressive medication
    → Rhodiola/Schisandra modulate immune tone.


No known harmful interactions at nutritional levels, but endocrine/corticosteroid considerations are clinically relevant.


8. Feeding Guidance

Dried Herb Blend:
5g per 100kg (25g/500kg horse).
1 level 15ml scoop ≈ 10g.

Organic Tincture:
6ml per 100kg (30ml/500kg horse).

Introduce gradually over 5–7 days.

Sensitivity Advisory:
If unexpected behavioural, digestive, or energy changes occur, discontinue and consult a veterinarian.


9. Clinical Considerations

Advisories

  • Designed for post-stress use, not acute anxiety.
  • Daily, consistent feeding recommended for recovery.
  • May be used long-term for emotional steadiness.
  • Suitable during rehabilitation, post-illness recovery, or winter fatigue.
  • Complementary to StressTonic/OptimaCARE protocols.

Contraindications

  • Pregnancy/lactation.
  • Horses on corticosteroid medication.
  • Concurrent use with other adrenal/calming blends without guidance.
  • Acute stress, reactivity, or panic (use StressTonic or CalmTonic instead).


10. Supporting Products

  • StressTonic — acute stress regulation
  • CalmTonic — short-term situational calm
  • OptimaCARE / OptimaPLUS — deep gut–stress reset
  • EquiVita / VitaComplete — nutritional foundation
  • VitaBoost — post-stress micronutrient support


11. Standard Professional Disclaimer

AdrenaVIVE is a botanical, nutritional food supplement for horses. It is not veterinary medicine and does not diagnose, treat, or prevent disease. Veterinary consultation is recommended for horses on concurrent medication or with endocrine concerns.