GUTAMINOS for Horses | Gut Lining & Leaky Gut Support

GutAminos is built around the fact that for the gut lining to renew itself, it needs the raw materials to do so.

T o support any cellular repair in the body, we need protein, which is broken down into amino acids required for cellular regeneration. And for a healthy gut membrane , two specific amino acids play a pivotal role in supporting the repair of this delicate tissue - L Glutamine and N-Acetyl L-Cysteine (NAC).

It's easy to think of "the gut" as a tube that digests food - but it's actually so much more than that.

The intestinal lining acts as one of the body's most important protective barriers, deciding what stays in, what gets absorbed, and how the immune system responds to the world passing through it every day.

And despite doing such an important job, it's only one single cell thick.

Yes you read that right - your horse's intestinal barrier is only one cell thick. That's an extraordinary amount of responsibility for such a delicate structure, which makes it extremely vulnerable to tears or ulcer wounds.

They're not there to "fix" the gut - they're there because the cells that make up the intestinal lining rely on them every day as part of their normal maintenance and renewal processes.

Supporting those processes can become particularly important following digestive upset - equine gastric ulcers or leaky gut in horses (permeable membrane), periods of stress, gastric ulcer challenges, antibiotic use, or any situation where the gut's natural barrier may be under additional pressure.

GutAminos is a good fit when the focus shifts from what's happening inside the gut to the health of the gut lining itself.

✔ Your horse is recovering from gastric ulcers, colic, or ongoing stomach sensitivity
✔ Faecal water, loose droppings, or hindgut sensitivity suggesting the intestinal barrier may need additional support
✔ Your horse is recovering after antibiotics
✔ You're supporting a horse with a history of gut challenges and want to nourish the tissues involved in repair and renewal

In short: GutAminos is the next step of a wider digestive support plan – providing targeted nutritional support for the cells that form the body's most important digestive barrier.

From there, support can be adapted depending on what you're seeing.

- Building on a gut reset

• SiboCARE – where microbial imbalance, gas, bloating, or hindgut instability are still active parts of the picture.
• DuoBute – where discomfort, sensitivity, or gut-related tension are part of the picture alongside microbial imbalance.
• StressTonic - if your horse is in a state of chronic stress.

For many horses, SiboCARE comes first, with GutAminos introduced once the gut environment has become calmer and more stable.

- Supporting gastric comfort

• KolicTonic - where spasmodic discomfort or gas-related tension are part of the picture, particularly following a mild colic episode.
• UlsaTonic – for ulcer-related patterns of stomach sensitivity and gastric discomfort.
• UlsaCOMBO – for horses needing broader support across gastric ulcer-related stress and tension.

- Supporting the wider recovery picture

• LKLCARE – often used after digestive challenges to support the liver, kidneys, and wider internal housekeeping (detoxing) systems.
• LeakyGutCOMBO – where microbial balance and gut-lining support are both required within one combined programme.

- Foundation support

Healthy digestive tissues rely on more than targeted nutrients alone. Supporting your horse's baseline nutrition with a forage-based mineral blend such as VitaComplete or EquiVita, alongside appropriate fibre and forage intake, helps provide the nutritional foundations that the gut lining depends upon for normal maintenance and renewal.

*If you're not already feeding a mineral balancer, try one of our 1kg trial bags.

In summary

Use GutAminos when the focus turns from stabilising the gut environment to nourishing the tissues that support long-term digestive resilience.

GutAminos is a nutritional food supplement and not veterinary medicine. For more on this, see Dr Kellon's article - Nutrition is not 'Alternative' Therapy .

Composition Glossary

Each ingredient in GutAminos plays a targeted role in maintaining your horse’s stomach comfort where additional support for the intestinal lining and wider digestive tract is needed.

• L-Glutamine – The preferred fuel of enterocytes (gut-lining cells), L-Glutamine supports epithelial repair, maintains pH balance, and helps restore the intestinal barrier after stress, illness, or inflammation. A key amino acid used by the cells that line the intestinal tract, playing an important role in the normal maintenance and renewal of the gut barrier.
• N-Acetyl L-Cysteine (NAC) – A bioavailable precursor to glutathione , the body’s master antioxidant. Protects gut and liver cells from oxidative stress, supports detoxification pathways, and works in tandem with L-Glutamine to enhance tissue regeneration.
• Althaea officinalis Radix – A mucilaginous herb rich in polysaccharides that coat, soothe, and protect the mucosal lining. Traditionally used for gastric ulcers, it helps calm irritation, supports epithelial growth, and strengthens the gut’s natural barrier function.

Feed guide

• 3g/100kg bodyweight per day, i.e. 15g for a 500kg horse.
• 1 level 15ml scoop = 15-grams.
• Amino acids manufactured to ISO, BP, USP & EP requirements and/or food grade specifications.

Energetic Architecture explains how a formula is structured to work in a balanced and purposeful way.

GutAminos focuses on nourishing the tissues that form the gut barrier itself - think of it as providing the bricks and mortar needed for ongoing maintenance and renewal.

Functional intent

GutAminos is designed to support:

• Intestinal lining health and renewal
• Gut barrier resilience and integrity
• Cellular nutrition for digestive tissues
• Antioxidant protection during tissue renewal
• Long-term digestive resilience

The goal is to provide nutritional support for the cells that maintain the gut barrier itself.

Functional categories – gut lining support in action

1. Cellular fuel for intestinal renewal - L-Glutamine
   - Providing a key fuel source for enterocytes - the specialised cells that line the intestinal tract.
2. Antioxidant & cellular resilience - N-Acetyl L-Cysteine (NAC)
   - Supporting glutathione production and helping maintain cellular resilience during periods of digestive challenge and recovery.
3. Mucosal comfort & barrier support - Althaea officinalis
   - Soothing, mucilage-rich support for the delicate tissues that line the digestive tract.
4. Nutritional support for tissue maintenance - L -Glutamine, N-Acetyl L-Cysteine
   - Supplying key nutritional building blocks for normal maintenance and renewal of digestive tissues.

Big picture

When we think about gut health, we tend to focus on what's inside the gut - the microbes, the feed, the droppings, the symptoms.

Yet all of that sits on top of a barrier that's only one cell thick.

GutAminos was created to support that barrier directly, providing targeted nutritional support for the cells that form one of the body's most important protective surfaces.

Put simply, resilient guts are built one cell at a time.

Advisories

• Best fed alongside SiboCARE or UlsaTonic for comprehensive intestinal and gastric membrane support.
• Hydration is essential: Ensure horses have constant access to clean water, as amino acids and mucilaginous herbs increase cellular water demand.
• Safe for long-term use as part of ongoing gut health management, especially following antibiotic use, colic recovery, or chronic stress.

Contraindications

• Always seek veterinary advice for pregnant or nursing mares due to limited safety data for NAC and Althaea officinalis in reproductive stages.

What is GutAminos designed to support?

GutAminos provides targeted nutritional support for the cells that form the intestinal lining and gut barrier.

It combines key amino acids with soothing botanical support to help nourish and maintain one of the body's most important protective surfaces.

What signs suggest my horse may benefit from GutAminos?

GutAminos is designed for when attention shifts from stabilising the gut environment to supporting the gut lining itself.

Common situations include:

✔ Recovery from gastric ulcers
✔ Faecal water or ongoing hindgut sensitivity
✔ Recovery following antibiotics
✔ Digestive disruption following periods of stress
✔ Horses needing additional support for long-term digestive resilience
✔ Rebuilding after a gut reset programme

GutAminos vs SiboCARE – what's the difference?

Although they are often used together, they serve different purposes.

SiboCARE focuses on supporting microbial balance and helping stabilise an unsettled hindgut environment.

GutAminos focuses on nourishing the intestinal lining itself and supporting the cells involved in ongoing maintenance and renewal.

In simple terms, SiboCARE helps stabilise the environment, while GutAminos helps support the barrier.

Should I feed SiboCARE or GutAminos first?

It depends on what's presenting, i.e. leaky gut/faecal water or gastric ulcers.

If the issues are hindgut microbial imbalance, gas, bloating, feed SiboCARE. If the symptoms are deeper, i.e. leaky gut/faecal water or gastric ulcers, GutAminos is introduced as the rebuilding phase to support the health and resilience of the gut lining.

Our LeakyGutCombo is also ideal for this scenario, which incorporates SiboCARE and GutAminos together.

GutAminos vs LeakyGutCOMBO – what's the difference?

GutAminos focuses specifically on providing targeted nutritional support for the intestinal lining.

LeakyGutCOMBO combines microbial support with gut-lining support in a single programme, making it a popular choice when both areas need addressing at the same time.

Can GutAminos be fed alongside UlsaTonic?

Yes. This is a common combination for horses where both stomach and intestinal support are needed, and is in fact covered in our UlsaCOMBO.

UlsaTonic focuses on gastric comfort and the stomach's natural protective systems, whilst GutAminos focuses on supporting the intestinal lining further along the digestive tract.

Can GutAminos be fed long term?

Yes. Many owners choose to use GutAminos as part of a longer-term digestive support programme, particularly following significant digestive challenges or where maintaining gut resilience is a priority.

What makes L-Glutamine so important?

L-Glutamine is widely recognised as a key fuel source for enterocytes - the specialised cells that line the intestinal tract.

These cells have a high demand for nutrients because they are constantly being renewed and replaced.

What is NAC and why is it included?

N-Acetyl L-Cysteine (NAC) is a precursor to glutathione , one of the body's most important antioxidant compounds.

It is included to support cellular resilience and to complement the role of L-Glutamine during periods of digestive recovery and renewal.

How quickly will I notice a difference?

Every horse is different - some owners notice improvements within a short time, i.e. the first week, whilst others see more gradual changes as part of a longer-term programme.

Because GutAminos works by supporting the cells involved in tissue maintenance and renewal, it is generally best viewed as a rebuilding nutrient rather than a quick fix.

Can GutAminos be fed after antibiotics?

GutAminos is recommended following antibiotic use as part of a wider digestive support programme.

The intestinal lining is one of the fastest-renewing tissues in the body and may benefit from targeted nutritional support during periods of recovery.

Do I still need a mineral balancer if I'm feeding GutAminos?

Yes. Targeted nutrients work best when the wider nutritional foundations are in place.

A forage-based mineral balancer such as VitaComplete or EquiVita helps provide the broader nutritional framework that healthy digestive tissues depend upon.